zz

جلوگیری از ریزش مو با مصرف گانودرما (ریشی)

مکانیسم اثر:

1. Reishi As An Inhibitor of DHT

جلوگیری از فعالیت آنزیم 5α-reductase

Dihydrotestosterone (DHT) is a sex hormone converted from testosterone by the enzyme known as 5α-reductase.

 This is a natural process, one which is not harmful to the majority of individuals. Men with a genetic predisposition to male-pattern baldness, however, are sensitive to DHT in the scalp. This is the leading cause of Androgenetic Alopecia (AGA).

 

Fortunately for sufferers of AGA, DHT inhibition is possible. With proper inhibition, hair loss may be reversible, and hair growth can occur in a natural, undisturbed manner.

 

One such manner is with reishi mushroom supplementation.

 

A 2005 Japanese study tested 19 species of mushroom to determine their 5α-reductase inhibitory effects.

 

First, researchers prepared ethanol extracts of each of the 19 mushroom species included in the experiment.

 

In the first part of this study, scientists added the ethanol extracts to a suspension containing rat liver and prostate microsomes. The purpose of this experiment was to determine percentage of inhibitory activity of each of the mushroom samples.

 

Reishi Mushroom inhibits 5-alpha-reductase, thereby reducing DHT levels in the scalp.

 

Reishi showed the most percentage of 5α-reductase inhibition, falling between 70 and 80%. For reference, the next most-effective mushroom species, pleurotus osteratus, showed an inhibitory percentage around 60%.

 

Next, researchers looked at the growth rate of prostates in castrated rats. As the prostate’s size is directly proportional to testosterone levels, this experiment aimed to determine whether G. lucidum (reishi mushroom) could inhibit testosterone’s effects.

 

Reishi works to reduce testosterone effects on Prostate growth.

 

The rats were split into three groups.

 

The first group was the control group, receiving only testosterone. The second group received both testosterone and G. lucidum (1.5 mg/kg), and the third group received both testosterone and a 15 mg/kg concentration of G. lucidum.

 

While the results did show that both concentrations of reishi reduced prostate weight below that shown in the testosterone control group, the lower concentration interestingly was more effective at doing so.

 

For those with hair problems sufferers, what should be the main takeaway from this study?

 

Chiefly, reishi mushroom is an effective inhibitor of 5α-reductase, thereby reducing the amount of DHT produced within the body.

 

For those with AGA, this is a critical find! It means that reishi mushroom supplementation can significantly reduce DHT levels, protecting the DHT-sensitive hair follicles from miniaturization.

 


Without the right nutrition you'll be fighting a losing battle. Get my 1-week Meal PlanPDF sent to your inbox, so you know exactly what to eat. Enter your email and I'll send you the PDF right away so you can keep reading this article.


 

2. Reishi As An Antimicrobial

 خاصیت صدف میکروبی گانودرما

With antibiotic resistance rapidly increasing, natural methods of fighting various microbes has quickly come to the forefront of scientific research.

 

Not surprisingly, reishi and other Chinese herb medicines have underwent extensive study. This is due to their thousands of years of use as part of Traditional Chinese Medicine.

 

In a study by Quereshi et al., reishi mushroom was collected, dried, crushed, and then extracted through one of three methods (methanol, ethanol, and acetone). In addition, a negative control (distilled water) and a positive control (the antibiotic Gentamycin sulphate) were also used.

 

Each of the five solutions was added to the plates of six different bacterial pathogens, and each plate was the incubated for 24 hours. Each of the tests was repeated three times, and the results were thus:

 

 

Now, while known of the reishi extracts didn’t exceed the positive control results of the antibiotic, some of them did come quite close. Namely, the acetone extract against both B. subtilis and K. Pneumoniae. Additionally, all extracts did show a zone of microbial inhibition over the negative control.

 

You may be wondering, “what good is an antimicrobial against hair loss?”

 

Consider that not all forms of alopecia are due to DHT sensitivity.

 

Other forms of hair loss exist, caused by such things as fungal infections and bacterial overgrowth.

 

 

With the addition of an antimicrobial agent like reishi mushroom to your hair care routine, not only can you ensure that your scalp stays healthy, but you can also keep your hair follicles from becoming blocked or clogged. This will ensure that your hair strands have the best environment in which to develop and grow.

 

3. Reishi As An Immunomodulator

 تقویت سیستم ایمنی با استفاده از گانودرما

One particular form of alopecia – alopecia areata – is an autoimmune form of baldness.

 

The immune system works to keep the body safe against foreign attacks. These attacks include viruses and bacteria.

 

The patchy scalp of an Alopecia Areata sufferer.

 

For those with alopecia areata, the immune system attacks the hair follicles, causing hairs to fall out and follicle damage. This leads to patchy hairs though, if left untreated, will lead to full hair loss over time.

 

There are a number of treatments which individuals with this type of alopecia undergo. And, while some may treat the hair issues at the time, it’s important for the root cause of the hair loss to be treated in order for a permanent solution to be found.

 

Is reishi such a permanent solution?

 

Well, reishi mushroom has proven to work as an immunomodulator. Essentially, this means that reishi can activate the immune system through chemical manipulation (in this case, cytokine production).

 

While no studies on reishi’s effect on alopecia areata currently exist, it isn’t a far jump to say that reishi may be beneficial in such treatment. After all, a proper immune response would lessen the attack on hair follicles and encourage the growth of healthy hair.

 

How to Use Reishi Mushroom Treatment

 

If you’re ready to experiment with reishi mushroom, you’ll be happy to know that there are a variety of methods you can try.

 

Make Your Own Reishi Shampoo

 نحوه ساخت شامپوی ریشی به صورت خانگی

Store-bought shampoos are full of chemicals and hard on your scalp. Combat this by making your own homemade shampoos.

 

Ingredients:

 

  • Liquid castile soap (½ cup)
  • Aloe vera gel (⅓ cup)
  • Green tea (½ cup)
  • Vanilla essential oil (10 drops)
  • Reishi extract (1 cup)

 

Directions:

 

Bring a pot of water to boil, removing from heat and adding in the reishi mushroom to steep. Allow to cool to room temperature, and then discard of reishi solids.

 

Combine the reishi tea with the rest of the ingredients, being sure to stir thoroughly.

 

Apply the shampoo to wet hair, taking 2-3 minutes to massage into the scalp. The shampoo can sit for up to 5 minutes, and then rinse completely in lukewarm water.

 

Hair Benefits:

 

This potent combination has a variety of nourishing elements, while also stimulating hair growth and promoting a clean scalp.

 

The aloe vera gel is the main soother in this recipe, protecting the scalp from irritation and itchiness.

 

The reishi (which inhibits 5α-reductase) and the vanilla oil extract (which stimulates hair growth) work together to contribute to a healthy environment in which hair can grow.

 

Last, the various compounds found within green tea promote further hair growth and provide a powerful punch of antioxidants.

 

Add It To a Hair Growth Mask

 While homemade shampoos are a fantastic start, you can always go the extra mile and create your own scalp scrubs, moisturizers, and even hair growth masks.

 

What You’ll Need:

 

  • Avocado (1 half)
  • Vanilla Essential Oil (10 drops)
  • Cherries (6, peeled and pitted)
  • Water (1/2 cup)
  • Herbs (nettle, chamomile, reishi)

 

Directions:

 

Bring a pot (or kettle) of water to boil. Remove from heat, and add in the nettle, chamomile, and reishi. Allow to steep until water reaches room temperature, then remove herbs.

 

Combine the herb and mushroom tea, with the avocado, cherries, and vanilla essential oil. Add to a blender and blend the mixture at high speed until smooth.

 

Apply the mask to wet hair and scalp. Massage the mask into your scalp for 2-3 minutes, and then allow to sit on scalp for 15-20 minutes. Rinse the mask with lukewarm water, and then towel dry.

 

Hair Benefits:

 

This nourishing and moisturizing hair mask will benefit your scalp in a number of ways.

 

Of course, the reishi acts as an inhibitor of 5α-reductase. The avocado provides a variety of nutrients, while simultaneously protecting the scalp from dryness. The cherries add in a boost of antioxidants, while the vanilla essential oil works to stimulate new hair growth.

 

Add It To Your Diet

 

If you’d rather not play chemist, then you can forego the creation of your own shampoos and hair masks and instead opt for the easy method of supplementation – adding it to your diet.

 

Of course, reishi makes an excellent tea while providing all of the many benefits mentioned above.

 

You can also add it to soups, salads, and even grill it for an appetizing and nourishing side dish.

 

Note: Prior to consuming, soak mushrooms overnight. This will soften the husk which surrounds the mushroom, without removing any of its nutrients.

 

Or you can take it as a supplement.

 

What’s the Bottom Line?

 

While there have yet to be any human studies done to determine reishi mushroom’s direct effects on hair growth, the current research does show promising results for those looking to treat their genetic baldness naturally.

 

Of course, combining reishi with other natural treatments, such as supplementation with pumpkin seed oil and primrose essential oil, can enhance results and improve your hair growth efforts over time.

  http://www.iranzaminmushroom.ir/post/1471



:: برچسب‌ها: جلوگیری از ریزش مو با مصرف گانودرما, ریشی
ن : دکتر ولی اله مهدیزاده
ت : پنجشنبه بیست و دوم شهریور ۱۳۹۷

مقاله 2018: بتا-دی گلوگان گنودرما لوسیدیوم (ریشی) و تاثیر آن روی سیستم ایمنی

خلاصه نتیجه (به رنگ سبز و آبی بلد): تکثیر و افزایش فعالیت عوامل موثر در تقویت سیستم ایمنی بدن

Triple helix conformation of β-D-glucan from Ganoderma lucidum and effect of molecular weight on its immunological activity

Abstract

β-D-glucan (GLP20) isolated from Ganoderma lucidum fruiting bodies was successfully fractionated into five fractions with different weight-average molecular weights (Mw) through ultrasonic irradiation. The Mw, radius of gyration (Rg), hydrodynamic radius (Rh) and intrinsic viscosity ([η]) of these fractions in phosphate buffered saline (PBS) aqueous solution were determined using HPSEC-MALLS-RI-VS system. The results indicated that β-D-glucan displayed rigid chain conformations with ρ values lager than 2.06 for the five fractions. By applying the polymer solution theory, the exponent (ν and α) values of Rg = kMwν and [η] = kMwα were calculated as 0.72 and 1.05, respectively, which confirmed the rigid chain conformation of glucans with Mw from 2.9 × 105 to 2.42 × 106 g mol−1. According to the known theory for chains, the molar mass per unit contour length ML, persistence length q and contour length h per main-chain glucose residue were estimated to be 2150 nm−1, 128 nm and 0.30 nm, respectively, which indicated that the glucan existed as triple-helical chains in PBS aqueous solution. Bioactivity study of glucan fractions on lymphocytes and THP-1 macrophages demonstrated that fractions with Mw higher than 1.82 × 106 g mol−1 exhibited better immunological activity. These fractions stimulated lymphocyte proliferation, promoted macrophages to form pseudopodia, and enhanced the levels of inflammatory cytokines IL-6 and TNF-α.

Keywords



:: موضوعات مرتبط: مقالات آموزشی قارچ
:: برچسب‌ها: مقاله 2018, بتا, دی گلوگان گنودرما لوسیدیوم, ریشی
ن : دکتر ولی اله مهدیزاده
ت : چهارشنبه یکم فروردین ۱۳۹۷

قارچ های موثر روی قند،  دیابت: مقالات و مطالب مرتبط در اینترنت



Fungal Diversity September 2012, Volume 56, Issue 1, pp 1–29

Medicinal mushrooms in prevention and control of diabetes mellitus

Abstract

Diabetes mellitus is a life-threatening chronic metabolic disease caused by lack of insulin and/or insulin dysfunction, characterized by high levels of glucose in the blood (hyperglycemia). Millions worldwide suffer from diabetes and its complications. Significantly, it has been recognized that type 2 diabetes is an important preventable disease and can be avoided or delayed by lifestyle intervention. Presently, there are many chemical and biochemical hypoglycemic agents (synthetic drugs), that are used in treating diabetes and are effective in controlling hyperglycemia. However, as they may have harmful side-effects and fail to significantly alter the course of diabetic complications, natural anti-diabetic drugs from medicinal plants have attracted a great deal of attention. Medicinal mushrooms have been valued as a traditional source of natural bioactive compounds over many centuries and have been targeted as potential hypoglycemic and anti-diabetic agents. Bioactive metabolites including polysaccharides, proteins, dietary fibres, and many other biomolecules isolated from medicinal mushrooms and their cultured mycelia have been shown to be successful in diabetes treatment as biological anti-hyperglycemic agents. In this review we discuss the biological nature of diabetes and, in particular, explore some promising mushrooms that have experimental anti-diabetic properties, preventing or reducing the development of diabetes mellitus. The importance of medicinal mushrooms as agents of medical nutrition therapy and how their metabolites can be used as supportive candidates for prevention and control of diabetes is explored. Future prospects for this field of study and the difficulties and constraints that might affect the development of rational drug products from medicinal mushrooms are discussed.

http://link.springer.com/article/10.1007/s13225-012-0187-4


Int J Med Mushrooms. 2011;13(5):401-26.

Medicinal mushrooms for glycemic control in diabetes mellitus: history, current status, future perspectives, and unsolved problems (review).

Abstract

Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia with defects in insulin secretion and/or insulin resistance. Despite great efforts that have been made in the understanding and management of diabetes, its prevalence continues to grow. Recent discoveries have opened up an exciting opportunity for developing new types of therapeutics from medicinal mushrooms to control DM and its complications. To date, more and more active components including polysaccharides and their protein complexes, dietary fibers, and other compounds extracted from fruiting bodies, cultured mycelium, or cultured broth of medicinal mushrooms have been reported as to having anti-hyperglycemic activity. These compounds exhibit their antidiabetic activity via different mechanisms. This article presents an overview of the multiple aspects of diabetes mellitus and the efficacy and mechanism of medicinal mushrooms for glucose control in diabetes, including the inhibition of glucose absorption, protection of beta-cell damage, increase of insulin release, enhancement of antioxidant defense, attenuation of inflammation, modulation of carbohydrate metabolism pathway, and regulation of insulin-dependent and insulin-independent signaling pathways. However, there is insufficient evidence to draw definitive conclusions about the efficacy of individual medicinal mushrooms for diabetes. In addition, the wide variability, the lack of standards for production, and the lack of testing protocols to assess product quality are still problems in producing medicinal mushroom products. Moreover, well-designed randomized controlled trials with long-term consumption are needed to guarantee the bioactivity and safety of medicinal mushroom products for diabetic patients.

https://www.ncbi.nlm.nih.gov/pubmed/22324407



Phytochemistry. 2015 Jun;114:109-13. doi: 10.1016/j.phytochem.2015.02.017. Epub 2015 Mar 16.

Anti-diabetic effects of Ganoderma lucidum.

Abstract

Ganoderma lucidum is a white rot fungus widely used as a tonic for the promotion of longevity and health. Extracts of G. lucidum have been recognized as an alternative adjuvant treatment for diabetes. Among the many biologically active constituents of G. lucidum, polysaccharides, proteoglycans, proteins and triterpenoids have been shown to have hypoglycemic effects. G. lucidum polysaccharides have been reported to have hypoglycemic activity by increasing plasma insulin levels and decreasing plasma sugar levels in mice. Protein tyrosine phosphatase 1B is a promising therapeutic target in diabetes, and G. lucidum proteoglycan can inhibit this enzyme in vitro. Moreover, G. lucidum triterpenoids were shown to have inhibitory activity on aldose reductase and α-glucosidase that can suppress postprandial hyperglycemia. In addition, a protein Ling Zhi-8 extracted from G. lucidum significantly decreased lymphocyte infiltration and increased the antibody detection of insulin in diabetic mice. This review summarizes most of the research about the hypoglycemic action effects of polysaccharides, proteoglycans, proteins and tritrerpenoids from G. lucidum as a guide for future research.


 

Reishi And Diabetes قارچ ریشی و دیابت

According to researchers from the Institute of Vascular Medicine at the Chinese University of Hong Kong, reishi mushrooms can lower blood sugar levels in laboratory animals.

For their study, which was published in the May 2009 edition of Phytomedicine, the researchers fed 0.03 and 0.3g/kg of reishi extracts to diabetic mice over a one-month period. The extracts lowered the blood glucose levels of the mice within a single week, leading the researchers to believe that the mushroom inhibits an enzyme used by the liver to produce glucose.

 

 

Another Chinese study, which was conducted by researchers at the Department of Pharmacology of Peking University in Beijing and published in the December 2006 issue of the Journal of Asian Natural Products Research, specifically looked into reishi's effects on diabetic kidney disease. After the eight-week trial period, the diabetic subjects exhibited noticeably reduced markers of kidney stress, as well as lowered triglyceride and blood sugar levels. The researchers concluded that reishi mushrooms can prevent or halt the progression of diabetic kidney complications.

Important: Unlike most other medicinal mushrooms, which can be eaten cooked, reishi have a tough texture that is difficult for our stomachs to digest. Therefore, if you're interested in utilizing reishi as a medicine, consider consuming it in extract form (like in the studies) for improved nutrient absorption. 

 


http://www.naturalnews.com/044163_reishi_mushrooms_shrink_tumors_cancer_treatment.html



The fourth herb is Ganoderma Lucidum. This herb helps to boost body energy and improve blood circulation. Therefore, Ganoderma Lucidum is one of the important herbs for diabetes.

Although Ganoderma Lucidum herb alone is not enough, it can help to improve your blood circulation and increase your immune system. This prevents the disease from worsening and also prevents other diabetes complications such as hypertension, stroke and foot ulcer.

The polysaccharides found in Ganoderma and Cordyceps are also proven to help insulin to transfer sugar into body cells.

http://www.ganoderma-for-health.com/herbs-for-diabetes.html


معرفی اثر چند قارچ مفید روی دیابت

http://www.positivehealth.com/article/diabetes/medicinal-mushrooms-natural-supplement-for-diabetics

http://edzardernst.com/2016/11/mushrooms-for-the-management-of-diabetes/

 

 


 

 

 



:: موضوعات مرتبط: فروش قارچ های دارویی
:: برچسب‌ها: قارچ های موثر روی قند, دیابت, گنودرما, ریشی
ن : دکتر ولی اله مهدیزاده
ت : جمعه چهارم فروردین ۱۳۹۶
 
برای مشاهده تعرفه خدمات مشاوره ای کلیک نمایید .

.:: کلیک کنید ::.
 
با کلیک روی +۱ ما را در گوگل محبوب کنید